PHARMACOTHERAPY

Volume 27 • Number 4 • 481 -- 618


SPECIAL ARTICLE
481 -- Clinical Pharmacy Services, Pharmacy Staffing, and Hospital Mortality Rates
C. A. Bond, Pharm.D., FASHP, FCCP, and Cynthia L. Raehl, Pharm.D., FASHP, FCCP

ORIGINAL RESEARCH ARTICLE
494 -- Adverse Events Associated with High-Dose Ribavirin: Evidence from the Toronto Outbreak of Severe Acute Respiratory Syndrome
Matthew P. Muller, M.D., FRCPC, Linda Dresser, Ph.D., Janet Raboud, Ph.D., Allison McGeer, M.D., FRCPC, Elizabeth Rea, Ph.D., Susan E. Richardson, M.D., FRCPC, Tony Mazzulli, M.D., FRCPC, Mark Loeb, M.D., FRCPC, and Marie Louie, M.D., FRCPC, for the Canadian SARS Research Network

RESEARCH REPORTS
504 -- Evaluation of Immunomodulatory Biomarkers in a Pressure Overload Model of Heart Failure
Barry E. Bleske, Pharm.D., FCCP, Hyun Seok Hwang, M.S., Issam Zineh, Pharm.D., Michael G. Ghannam, and Marvin O. Boluyt, Ph.D.

510 -- Symptom-Driven Lorazepam Protocol for Treatment of Severe Alcohol Withdrawal Delirium in the Intensive Care Unit
Douglas D. DeCarolis, Pharm.D., Kathryn L. Rice, M.D., Libin Ho, M.D., Ph.D., Mark L. Willenbring, M.D., and Susan Cassaro, R.N.

519 -- Clinical Utility of a Continuous Intravenous Infusion of Valproic Acid in Pediatric Patients
Lisa M. Taylor, Pharm.D., Farjam Farzam, M.D., Aaron M. Cook, Pharm.D., Daniel A. Lewis, Pharm.D., Robert J. Baumann, M.D., and Robert J. Kuhn, Pharm.D.

526 -- Angiotensin II Receptor Blockers for the Treatment of Heart Failure: A Class Effect?
Marie Hudson, M.D., M.P.H., Karin Humphries, M.Sc., M.B.A., D.Sc., Jack V. Tu, M.D., Ph.D., Hassan Behlouli, Ph.D., Richard Sheppard, M.D., and Louise Pilote, M.D., M.P.H., Ph.D.

535 -- Comparison of Darbepoetin alfa and Epoetin alfa in the Management of Anemia of Critical Illness
Stacy A. Voils, Pharm.D., Spencer H. Harpe, Ph.D., Pharm.D., M.P.H., and Gretchen M. Brophy, Pharm.D., FCCP, FCCM

REVIEWS OF THERAPEUTICS
542 -- Penicillin Allergy Skin Testing: What Do We Do Now?
Jeremy A. Schafer, Pharm.D., Noe Mateo, M.D., Garry L. Parlier, D.Ph., M.H.A., and John C. Rotschafer, Pharm.D.

546 -- Safety of Newer Antidepressants in Pregnancy
Cynthia M. Way, B.Sc.Pharm.

553 -- Contemporary Issues in Clopidogrel Therapy: New Evidence Shaping Clinical Practice
Kristi L. Emmons, Pharm.D., and Nicole R. Taylor, Pharm.D.

564 -- Heparin-Induced Thrombocytopenia: Treatment Options and Special Considerations
William E. Dager, Pharm.D., FCSHP, John A. Dougherty, M.B.A., Pharm.D., Phuong H. Nguyen, Pharm.D., Michael A. Militello, Pharm.D., and Maureen A. Smythe, Pharm.D., FCCP

588 -- Atypical Antipsychotics versus Haloperidol for Treatment of Delirium in Acutely Ill Patients
Rhonda S. Rea, Pharm.D., Sarah Battistone, Jeffrey J. Fong, Pharm.D., and John W. Devlin, Pharm.D., FCCM, FCCP

595 -- Cinnamon Supplementation in Patients with Type 2 Diabetes Mellitus
Antony Q. Pham, B.S., Helen Kourlas, Pharm.D., and David Q. Pham, Pharm.D.

CASE REPORTS
600 -- Diltiazem-Induced Eosinophilic Pleural Effusion
Lampros Raptis, M.D., Georgios Pappas, M.D., Andromahi Katsanou, M.D., Freideriki Koutsouka, M.D., Dimitrios Petrakis, M.D., and Nikolaos Akritidis, M.D.

603 -- Simvastatin-Associated Rhabdomyolysis After Coadministration of Macrolide Antibiotics in Two Patients
Espen Molden, Ph.D., and Kirsti Svendsen Andersson, M.D.

608 -- Rhabdomyolysis and Necrotic Bowel After Acetaminophen and Ibuprofen Overdose
Holli Nelson, Pharm.D., Daniel Katz, M.D., Ty Dunn, M.D., Gajendra Singh, M.D., Michael Voigt, M.D., Eric Whitaker, Pharm.D., and David Thomsen, B.S.

613 -- Safe Administration of Iron Sucrose in a Patient with a Previous Hypersensitivity Reaction to Ferric Gluconate
Radhika Sane, Pharm.D., David Baribeault, B.S., and Carol L. Rosenberg, M.D.

616 -- Fatal Pulmonary Toxicity After a Single Dose of Cyclophosphamide
Shilpa Gupta, M.B.B.S., and Amit Mahipal, M.B.B.S.